Welcome to the Holiday Inn Express® hotel in Lexington, South Carolina, which is just minutes from major interstates I-20 and I-26. Our beautiful property is centrally located in this small town and i
FROM 1-20 WESTBOUND, TAKE HWY378 TO LEXINGTON (EXIT 61). FROM I-20 EASTBOUND, TAKE EXIT 55 (HWY 6) TO HWY 378. FROM I-26, TAKE EXIT 110 (HWY 378) TO LEXINGTON 7 MI.